A growing body of evidence has revealed that microRNA (miRNA) expression is
dysregulated in cancer, and they can act as either oncogenes or suppressors under certain …

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, whereas acute
myeloid leukemia (AML) is the most common acute leukemia in adults. In general, ALL has a …

MicroRNAs (miRNAs), a new class of noncoding RNAs, which can hybridize to target
messenger RNAs and regulate their expression posttranscriptionally, express differentially …

We investigated the mechanism of action of LBH589, a novel broad-spectrum HDAC
inhibitor belonging to the hydroxamate class, in Philadelphia chromosome–negative (Ph−) …

Adiponectin, an adipocyte-specific secretory protein known to induce apoptosis, has been
reported to be inversely related to breast and endometrial cancers and recently found to …

Recent biologic advancements are progressively realising the possibility of designing
targeted and individualized therapeutic strategies according to the more refined, molecularly …

Acute lymphoblastic leukemia (ALL) is a heterogeneous cancer commonly affecting children
due to dysregulation of miRNA expression. In the current study, authors investigated the …

Acute lymphoblastic leukemia (ALL) is the most common kind of pediatric cancer. Although
the cure rates in ALL have significantly increased in developed countries, still 15–20% of …

This chapter describes the diseases of the orbit, lacrimal gland, and the lacrimal drainage
system. The embryology and anatomy of these structures is described shortly. All disease …

Different therapeutic methods have been developed for the B-cell and T-cell subtypes of
acute lymphoblastic leukemia (ALL). The identification of molecular biomarkers that can …