Black pepper and health claims: a comprehensive treatise
MS Butt, I Pasha, MT Sultan… - Critical reviews in …, 2013 - Taylor & Francis
For millennia, spices have been an integral part of human diets and commerce. Recently,
the widespread recognition of diet-health linkages bolsters their dietary importance. The …
the widespread recognition of diet-health linkages bolsters their dietary importance. The …
[HTML][HTML] Antitumor potential of immunomodulatory natural products
G Nuzzo, G Senese, C Gallo, F Albiani, L Romano… - Marine Drugs, 2022 - mdpi.com
Cancer is one of the leading causes of death globally. Anticancer drugs aim to block tumor
growth by killing cancerous cells in order to prevent tumor progression and metastasis …
growth by killing cancerous cells in order to prevent tumor progression and metastasis …
Piperine, an alkaloid from black pepper, inhibits growth of human colon cancer cells via G1 arrest and apoptosis triggered by endoplasmic reticulum stress
PB Yaffe, MR Power Coombs… - Molecular …, 2015 - Wiley Online Library
Piperine, a piperidine alkaloid present in black pepper, inhibits the growth of cancer cells,
although the mechanism of action is not well understood. In this study, we show that piperine …
although the mechanism of action is not well understood. In this study, we show that piperine …
[HTML][HTML] Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition
The mortality and morbidity rates of pancreatic cancer are high because of its extremely
invasive and metastatic nature. Its lack of symptoms, late diagnosis and chemo–resistance …
invasive and metastatic nature. Its lack of symptoms, late diagnosis and chemo–resistance …
In Vitro Investigation of the Potential Immunomodulatory and Anti-Cancer Activities of Black Pepper (Piper nigrum) and Cardamom (Elettaria cardamomum)
AF Majdalawieh, RI Carr - Journal of Medicinal Food, 2010 - liebertpub.com
Although the immunomodulatory effects of many herbs have been extensively studied,
research related to possible immunomodulatory effects of various spices is relatively scarce …
research related to possible immunomodulatory effects of various spices is relatively scarce …
Pro-oxidant natural products as anticancer agents
C Martin-Cordero, A Jose Leon-Gonzalez… - Current drug …, 2012 - ingentaconnect.com
Cancer cells produce high levels of reactive oxygen species (ROS) that lead to a state of
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …
increased basal oxidative stress. Since this state of oxidative stress makes cancer cells …
[HTML][HTML] Resveratrol from dietary supplement to a drug candidate: An assessment of potential
S Khattar, SA Khan, SAA Zaidi, M Darvishikolour… - Pharmaceuticals, 2022 - mdpi.com
Resveratrol (RVT) is a well known phyto-chemical and is widely used in dietary supplements
and botanical products. It shows a wide range of pharmacological/beneficial effects …
and botanical products. It shows a wide range of pharmacological/beneficial effects …
[HTML][HTML] Overview of the Anticancer Potential of the “King of Spices” Piper nigrum and Its Main Constituent Piperine
The main limits of current anticancer therapy are relapses, chemoresistance, and toxic
effects resulting from its poor selectivity towards cancer cells that severely impair a patient's …
effects resulting from its poor selectivity towards cancer cells that severely impair a patient's …
[HTML][HTML] Piperine, a bioactive component of pepper spice exerts therapeutic effects on androgen dependent and androgen independent prostate cancer cells
A Samykutty, AV Shetty, G Dakshinamoorthy… - PLoS …, 2013 - journals.plos.org
Prostate cancer is the most common solid malignancy in men, with 32,000 deaths annually.
Piperine, a major alkaloid constituent of black pepper, has previously been reported to have …
Piperine, a major alkaloid constituent of black pepper, has previously been reported to have …
[HTML][HTML] Curcumin sensitizes silymarin to exert synergistic anticancer activity in colon cancer cells
A Montgomery, T Adeyeni, KK San, RM Heuertz… - Journal of …, 2016 - ncbi.nlm.nih.gov
We studied combinatorial interactions of two phytochemicals, curcumin and silymarin, in
their action against cancer cell proliferation. Curcumin is the major component of the spice …
their action against cancer cell proliferation. Curcumin is the major component of the spice …