In vitro infection models to study fungal–host interactions

A Last, M Maurer, A S. Mosig… - FEMS Microbiology …, 2021 - academic.oup.com
Fungal infections (mycoses) affect over a billion people per year. Approximately, two million
of these infections are life-threatening, especially for patients with a compromised immune …

Spatial and temporal transcriptomics of Schistosoma japonicum-induced hepatic granuloma formation reveals novel roles for neutrophils

C Chuah, MK Jones, ML Burke… - Journal of leukocyte …, 2013 - academic.oup.com
The severity of schistosome egg-induced hepatic granulomatous pathology depends
markedly on the nature of the host immune responses. In this study, we used LMM and …

[PDF][PDF] Fabrication of a new all-in-one microfluidic dielectrophoresis integrated chip and living cell separation

K Oshiro, Y Wakizaka, M Takano, T Itoi, H Ohge… - Iscience, 2022 - cell.com
Microfluidic dielectrophoresis (DEP) technology has been applied to many devices to
perform label-free target cell separation. Cells separated by these devices are used in …

Whose gene is it anyway? The effect of preparation purity on neutrophil transcriptome studies

HB Thomas, RJ Moots, SW Edwards, HL Wright - PloS one, 2015 - journals.plos.org
Protocols for the isolation of neutrophils from whole blood often result in neutrophil
preparations containing low numbers (~ 5%) of contaminating leukocytes, and it is possible …

Oral neutrophils display a site‐specific phenotype characterized by expression of T‐cell receptors

FS Lakschevitz, GM Aboodi… - Journal of …, 2013 - Wiley Online Library
Background: Neutrophils, key cells of the innate immune system, were previously thought to
be terminally differentiated cells, incapable of altering their gene expression after …

Clinical immunology Expression of CD11b and CD18 on polymorphonuclear neutrophils stimulated with interleukin-2

BKA Abdel-Salam, H Ebaid - Central European Journal of Immunology, 2014 - termedia.pl
Background: Interleukin-2 (IL-2) is a lymphocyte-activating and growth-promoting factor, and
has been widely studied on T-cells and NK-cells. However, the interaction of …

An essential role of syntaxin 3 protein for granule exocytosis and secretion of IL-1α, IL-1β, IL-12b, and CCL4 from differentiated HL-60 cells

I Naegelen, S Plancon, N Nicot, T Kaoma… - Journal of Leucocyte …, 2015 - academic.oup.com
Besides their roles in the killing of pathogens, neutrophils have the capacity to package a
variety of cytokines into cytoplasmic granules for subsequent release upon inflammatory …

Ex vivo observation of Pythium insidiosum-antigen treated neutrophils on three Pythium insidiosum strains isolated from vascular pythiosis patients

S Medhasi, A Sriwarom, N Permpalung… - Human Vaccines & …, 2024 - Taylor & Francis
The mechanisms of Pythium insidiosum-antigen (PIA) immunotherapy activating a patient's
immune system are unknown. We evaluated the interleukin-8 (IL-8) serum levels during P …

Changes in CD73, CD39 and CD26 expression on T-lymphocytes of ANCA-associated vasculitis patients suggest impairment in adenosine generation and turn-over

L Kling, U Benck, A Breedijk, L Leikeim… - Scientific Reports, 2017 - nature.com
Extracellular adenosine, generated via the concerted action of CD39 and CD73, contributes
to T-cell differentiation and function. Adenosine concentrations are furthermore influenced …

[PDF][PDF] Neutrophil extracellular traps formation in patients with eosinophilic granulomatosis with polyangiitis: association with eosinophilic inflammation

J Natorska, M Ząbczyk, J Siudut, P Krawiec… - Clin Exp …, 2017 - clinexprheumatol.org
Objective. Eosinophilic granulomatosis with polyangiitis (EGPA) is associated with an
inflammation and the presence of antineutrophil cytoplasmic antibodies (ANCA). Thus, we …