Venous Thrombosis with Both Heterozygous Factor V Leiden (R507Q) and Factor II (G20210A) Mutations

F Bhaijee, B Jordan, DJ Pepper… - American Society for …, 2012 - clsjournal.ascls.org
Both hereditary and acquired factors increase the risk of venous thromboembolism, thus the
clinical management of affected patients involves evaluation of genetic factors that …

Risk of venous thromboembolism in carriers of factor V Leiden with a concomitant inherited thrombophilic defect: a retrospective analysis

JR Meinardi, S Middeldorp, PJ de Kam… - Blood coagulation & …, 2001 - journals.lww.com
Factor V Leiden is the most common genetic defect associated with venous
thromboembolism. Its clinical expression is limited and shows a wide intrafamilial and …

Combined effect of factor V Leiden and prothrombin 20210A on the risk of venous thromboembolism

J Emmerich, FR Rosendaal, M Cattaneo… - Thrombosis and …, 2001 - thieme-connect.com
Factor V Leiden and factor II G20210A mutations are two frequent genetic risk factors
involved in venous thromboembolism (VTE). The goal of this pooled analysis of 8 case …

[CITATION][C] Coinheritance of factor V Leiden (F5 1691A) and prothrombin 20210 A (F2 20210A) in an Austrian family as cause for early onset of venous …

M Brodmann, W Renner, G Stark… - Thrombosis …, 2001 - thrombosisresearch.com
Factor V Leiden (F5 1691A) and prothrom-bin 20210 A (F2 20210A) are established risk
factors for venous thrombembolism, with factor V Leiden as the most commonly inherited …

Risk of recurrent venous thrombosis in homozygous carriers and double heterozygous carriers of factor V Leiden and prothrombin G20210A

WM Lijfering, S Middeldorp, NJGM Veeger… - Circulation, 2010 - Am Heart Assoc
Background—Homozygous or double heterozygous factor V Leiden and/or prothrombin
G20210A is a rare inherited thrombophilic trait. Whether individuals with this genetic …

[HTML][HTML] Double-homozygosity for Factor V Leiden and Prothrombin c.* 97G> A Mutation in a Young Female with Recurrent Fetal Losses and no Venous …

I Abukhiran, J Jasser, S Bhagavathi - Human pathology: case reports, 2020 - Elsevier
Abstract Factor V Leiden (FVL) and factor II c.* 97G> A mutation are the two most common
genetic factors predisposing to hereditary thrombophilia. Being extremely rare, it used to be …

Phenotypic presentation of thrombophilia in double heterozygote for factor v leiden and prothrombin 20210 G> A mutations: Case report

L Nagorni-Obradović, N Maksimović, P Miljić… - Genetika, 2014 - doiserbia.nb.rs
Physicians usually do not suspect pulmonary thromboembolism in younger patients except
in those who have thrombophilia. In those latter patients some special conditions such as …

Multiplex PCR-RFLP assay for detection of factor V Leiden and prothrombin G20210A

I Baris, V Koksal, O Etlik - Genetic Testing, 2004 - liebertpub.com
Factor V Leiden and prothrombin G20210A are clinically relevant genetic risk factors for
venous thrombosis. Molecular diagnostic testing for factor V Leiden and prothrombin …

[HTML][HTML] The risk of recurrent deep venous thrombosis among heterozygous carriers of both factor V Leiden and the G20210A prothrombin mutation

V De Stefano, I Martinelli, PM Mannucci… - … England Journal of …, 1999 - Mass Medical Soc
Background Point mutations in the factor V gene (factor V Leiden) and the prothrombin gene
(the substitution of A for G at position 20210) are the most common causes of inherited …

Type and location of venous thromboembolism in carriers of Factor V Leiden or prothrombin G20210A mutation versus patients with no mutation

M Kovac, G Mitic, Z Mikovic… - Clinical and Applied …, 2010 - journals.sagepub.com
Factor V Leiden (FVLeiden) and prothrombin G20210A are the most common genetic
causes of thrombophilia and established risk factors for different clinical manifestations of …