Infections resistant to many or all antimicrobials are occurring globally, nationally, and
locally. Resistance is mediated through common, and often communicable, mechanisms …

The current collection of reviews in this inaugural issue on antimicrobial research belies the
fact that many pharmaceutical companies are no longer researching new antibiotics …

One of the most challenging aspects of infectious diseases is the recent emergence of
several bacterial pathogens that are resistant to conventional antibiotic therapy. In some …

Antibiotic Resistance — Problems, Progress, and Prospects | NEJM Skip to main content NEJM
Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …

Pathogenic bacteria employ a wide range of mechanisms to resist the toxic effects of the
many antimicrobial agents that we use to treat infected patients. We now have extensive …

The emergence of antibiotic-resistant bacteria is a serious threat to public health. Infectious
drug resistance, the transmission of resistant determinants from antibiotic-resistant bacteria …

For many years, physicians and the public assumed that the discovery of new antimicrobial
agents would outpace the ability of bacteria to mutate and develop drug resistance. Yet the …

Resistance to antimicrobial agents is emerging in a wide variety of nosocomial and
community-acquired pathogens. The emergence and spread of multiply resistant organisms …

The discovery, commercialization, and routine administration of antimicrobial compounds to
treat infections revolutionized modern medicine and changed the therapeutic paradigm …

The emergence of resistance to antimicrobial agents continues to be a major problem
among both nosocomial and community-acquired pathogens. Bacteria employ a variety of …