Objectives The aims of the study were to perform an instrument validation of the HemosIL
HIT-Ab (PF4-H) Assay and to compare the sensitivities and specificities of the three HIT tests …

The diagnosis of heparin-Induced thrombocytopenia (HIT) is based on the presence of a
compatible clinical picture combined with laboratory evidence of heparin-dependent …

Objectives Heparin-induced thrombocytopenia (HIT) is a rare but life-threatening condition
that requires rapid diagnosis for proper management. Laboratory testing should only be …

Heparin-induced thrombocytopenia (HIT) is an iatrogenic immune thrombotic disorder in
which platelet activating antibodies are mainly induced by heparin-platelet factor 4 (H-PF4) …

In May 2004, the United States Food and Drug Administration approved for marketing the
HealthTEST® Heparin/Platelet Factor 4 Antibody Assay (Akers Biosciences, Inc., Thorofare …

Introduction: The diagnosis of heparin induced thrombocytopenia (HIT) and thrombosis
(HITT) is challenging due to poor availability of the gold standard serotonin releasing assay …

Abstract The PF4-dependent P-Selectin Expression Assay (PEA) is a novel assay for
diagnosis of heparin-induced thrombocytopenia (HIT) which, in preliminary testing …

Introduction: Antibodies that cause heparin-induced thrombocytopenia (HIT) can be
detected with either antigenic or functional assays. Previously, it has been shown that …

Introduction Diagnosis of heparin-induced thrombocytopenia (HIT) usually requires
detecting anti-platelet factor 4/heparin antibodies, particularly the IgG isotype (anti-PF4/H …

Background Almost without exception, patients with heparin-induced thrombocytopenia/
thrombosis (HIT) have antibodies that recognize platelet factor 4 (PF4) in a complex with …