Troponin (Tn) is a heterotrimeric protein containing three subunits (C, T, and I) with different
molecular weights and distinctive functions. The subunits of Tn work cohesively to regulate …

The regulatory protein troponin (Tn) located on actin filament consists of three subunits: TnT–
binds troponin to tropomyosin, TnC–binds divalent calcium ions, and TnI–affects myosin …

Troponin-mediated Ca2+-regulation governs the actin-activated myosin motor function
which powers striated (skeletal and cardiac) muscle contraction. This review focuses on the …

The contractile sarcomeric pool of skeletal muscle and heart consists of a highly-ordered
arrangement of actin thin filaments, tropomyosin and proteins of the troponin complex …

Troponin T, which links the troponin complex to tropomyosin, is found as multiple isoforms in
the hearts of many animal species. Changes in isoform composition have been correlated …

Troponins are thin myofilament proteins that regulate the contraction of cardiac and skeletal
muscle. The cardio-specific troponin I (TnI) and T (TnT) proteins are sensitive and specific …

The troponin complex is located on the thin filament of striated muscle and is composed of
three component polypeptides: troponin T, troponin I, and troponin C. Three troponin T …

Troponin I (TnI) is the inhibitory subunit of the troponin complex in the sarcomeric thin
filament of striated muscle and plays a central role in the calcium regulation of contraction …

Troponin T (TnT) is present in striated muscle of vertebrates and invertebrates as a group of
homologous proteins with molecular weights usually in the 31–36kDa range. It occupies a …

In striated muscle, the protein troponin complex turns contraction on and off in a calcium-
dependent manner. The calcium-sensing component of the complex is troponin C, which is …