The objective of this study was to develop a diagnostic testing method to detect HbS,
distinguish sickle cell homozygotes from heterozygotes, and overcome testing barriers …

The aim of the study is to evaluate the stability and longevity of the paper-based screening
test for the sickle cell disease in relation to different temperatures and storage time. Blood …

OBJECTIVE: The purpose of this study is to estimate the prevalence of sickle hemoglobin in
northern Haiti. DESIGN: Sickle cell testing occurred from 2002-2009. Blood samples from …

Background Sickle‐cell anemia (SCA) is the most common genetic disease worldwide
caused by a single mutation in the gene HBB. DNA testing can help to clarify the diagnosis …

Sickle cell disease (SCD) is a common and life-threatening inherited disorder of
hemoglobin, affecting over 400,000 newborns annually. The majority of these births occur in …

Abstract In sub-Saharan Africa, nearly a quarter of a million babies are born with sickle cell
disease (SCD) each year. An estimated 50-90% of these babies die before age 5 due to lack …

Background-Sickle cell anemia is one of the most common heritable hematologic diseases
affecting humans. Detection of the single base pair mutations at codon 6 of the BETA …

Hemoglobin S (HbS), which causes sickle cell disease, is now the most common genetic
abnormality observed in France. Sickle cell disease is a generic term covering all the …

Sickle cell disease is a hereditary disease that predominantly affects black people. It is very
widespread in sub-Saharan Africa, particularly at the Lehmann “sickle belt” level, where the …

Background Sickle cell disease (SCD) is an important cause of< 5 mortality. In Tanzania, it is
estimated up to 11 000 children are born with SCD annually, making this the fifth country …