CD4 + regulatory T cells play a critical role in tolerance induction in transplantation. CD8 +
suppressor T cells have also been shown to control alloimmune responses in preclinical and …

We have previously shown that preemptive infusion of apoptotic donor splenocytes treated
with the chemical cross-linker ethylcarbodiimide (ECDI-SPs) induces long-term allograft …

Several studies have shown that recipient-derived CD4 + CD25 + Foxp3 + regulatory T cells
(Tregs) are involved in transplantation tolerance. However, it is not clear whether allogeneic …

The myeloid differentiation protein 88 (MyD88) adapter protein is an important mediator of
kidney allograft rejection, yet the precise role of MyD88 signaling in directing the host immune …

The major objectives of tumor vaccination are to induce the regression of established tumors
and to favor the establishment of long-lasting tumor-specific immunity, capable of protecting …

Adoptive T cell therapy has proven to be beneficial in a number of tumor systems by targeting
the relevant tumor antigen. The tumor antigen targeted in our model is Mammaglobin-A, …

The major driving force in the pathogenesis of pre-diabetes and Type 2 Diabetes is thought
to be chronic and low grade systemic inflammation. Immune cells are key players in the …

Several studies have demonstrated the presence of different populations of T cells involved
in the regulation of T-cell mediated allogeneic immune responses. Among these, CD4+ …

119-P: Induction of transplantation tolerance by allogeneic donor-derived CD4+CD25+Foxp3+
regulatory T cells × Close The Infona portal uses cookies, ie strings of text saved by a browser …

… This dissertation is dedicated to my grandfather Loren Lerret. Your love, kindness and faith
in me combined with the morals you instilled upon me have shaped me into the person I am …