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Research ArticleFocus: Body Fluids

Miscellaneous Findings in Body Fluids

Leilani Collins
American Society for Clinical Laboratory Science January 2009, 22 (1) 54-55; DOI: https://doi.org/10.29074/ascls.22.1.54
Leilani Collins
is associate professor, Clinical Laboratory Science Program, University of Tennessee Health Sciences Center, Memphis TN
MS MT(ASCP)SH CLS(NCA)
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  • For correspondence: lcollins@utmem.edu
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  1. Leilani Collins, MS MT(ASCP)SH CLS(NCA)⇑
    1. is associate professor, Clinical Laboratory Science Program, University of Tennessee Health Sciences Center, Memphis TN
  1. Address for correspondence: Leilani Collins MS MT(ASCP)SH CLS(NCA), associate professor, Clinical Laboratory Science Program, University of Tennessee Health Sciences Center, 930 Madison Avenue, Suite 670, Memphis TN 38163. (901) 448-6299. lcollins{at}utmem.edu.
  1. Describe the significance of eosinophils in urine.

  2. Describe lupus erythematosus cells in serous and synovial fluids.

  3. Describe the significant cellular findings in bronchial alveolar lavage (BAL) specimens.

Extract

Cytocentrifuge slides can provide important information in diagnosing various conditions.

Urine for eosinophils Urine samples for eosinophils may be submitted when interstitial nephritis secondary to antibiotic therapy is suspected. Slides to search for eosinophils should be prepared by concentration of the sample by either standard centrifugation or cytocentrifugation. Slides should be stained with Wright stain and a thorough search made for eosinophils. A finding of any eosinophils is significant.

Lupus Erythematosus (LE) cells LE cells are neutrophils containing a smooth homogeneous nuclear mass. The nucleus of the neutrophil will be displaced to the edge of the cell wall by the large homogeneous mass. In patients who have systemic lupus erythematosus, the characteristic LE cell may be seen in serous and synovial fluids. All the factors necessary for formation of these cells—incubation, trauma to the cells, and the LE factor—are present in vivo in patients with systemic lupus erythematosus. The finding of these cells can be of diagnostic significance in patients not previously identified with this disease. See Figure 1.

Bronchoalveolar lavage (BAL)—the fluid that isn't a fluid Bronchoalveolar lavage (BAL) is usually performed on hospitalized patients who have non-resolving pneumonia in an attempt to identify organisms that are not responding to antibiotic treatment or to detect malignancy. The “fluid” is obtained by introducing warmed saline into the lungs through a bronchoscope in 20 mL aliquots followed by aspiration of the saline. A total of 100-120 mL of saline is introduced and aspirated with a recovery of 40-60 mL.3 The “fluid”…

ARDS = adult respiratory distress syndrome; BAL = bronchoalveolar lavage; LE = Lupus Erythematosus.

    INDEX TERMS
  • body fluids
  • cerebrospinal
  • serous
  • synovial
  1. Describe the significance of eosinophils in urine.

  2. Describe lupus erythematosus cells in serous and synovial fluids.

  3. Describe the significant cellular findings in bronchial alveolar lavage (BAL) specimens.

  • © Copyright 2009 American Society for Clinical Laboratory Science Inc. All rights reserved.
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American Society for Clinical Laboratory Science: 22 (1)
American Society for Clinical Laboratory Science
Vol. 22, Issue 1
Winter 2009
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Miscellaneous Findings in Body Fluids
Leilani Collins
American Society for Clinical Laboratory Science Jan 2009, 22 (1) 54-55; DOI: 10.29074/ascls.22.1.54

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Miscellaneous Findings in Body Fluids
Leilani Collins
American Society for Clinical Laboratory Science Jan 2009, 22 (1) 54-55; DOI: 10.29074/ascls.22.1.54
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More in this TOC Section

  • Introduction
  • Examination of Body Fluids: Evaluating Gross Appearance; Performing Cell Counts
Show more Focus: Body Fluids

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Keywords

  • body fluids
  • cerebrospinal
  • serous
  • synovial

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