Hyperosmolar Hyperglycemic Syndrome with Rhabdomyolysis

Mary E. Stunkard; Valerie T. Pikul; Kevin Foley

doi:10.29074/ascls.24.1.8

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Mary E. Stunkard, PhD⇑
1. Department of Clinical Sciences, Northern Michigan University, Marquette, MI
Valerie T. Pikul
1. Department of Clinical Sciences, Northern Michigan University, Marquette, MI
Kevin Foley, PhD, MT
1. Kaiser Permanente Northwest Regional Laboratory, Portland, OR

Address for correspondence: Mary E. Stunkard PhD, Northern Michigan University, 1401 Presque Isle Avenue, 3511 West Science Building, Marquette, MI, 49855, 906-227-1662, mstunkar{at}nmu.edu.

Abstract

In this report we describe a patient who presented with nausea, vomiting, diarrhea, tachypnea and mental impairment. The patient had elevated serum lipase, troponin-I, creatinine kinase and myoglobin along with severe hyperglycemia (> 2000 mg/dl) and no ketouria. This patient was found to have nonketotic hyperosmolar hyperglycemia with concomitant rhabdomyolysis and myocardial infarction.

ABBREVIATIONS: CK, creatine phosphokinase, CT, computed axial tomography, DKA, diabetic ketoacidosis, HHS, hyperosmolar hyperglycemic syndrome, BUN, blood urea nitrogen, GFR, glomerular filtration rate, TnI, troponin-I, WBC, white blood cell count.