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Research ArticleResearch and Reports

Acute Myocardial Infarction: Definition, Diagnosis, and the Evolution of Cardiac Markers

Ana Oliveira, Krystle Glasgow, Floyd Josephat, Robert Estes, Remo George, Tosi Gilford, Samantha Giordano, Heather Hallman, Wei Li, Neena Xavier and Janelle Marie Chiasera
American Society for Clinical Laboratory Science October 2018, 31 (4) 200-204; DOI: https://doi.org/10.29074/ascls.2018000687
Ana Oliveira
University of Alabama at Birmingham
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Krystle Glasgow
University of Alabama at Birmingham
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Floyd Josephat
University of Alabama at Birmingham
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Robert Estes
University of Alabama at Birmingham
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Remo George
University of Alabama at Birmingham
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Tosi Gilford
University of Alabama at Birmingham
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Samantha Giordano
University of Alabama at Birmingham
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Heather Hallman
University of Alabama at Birmingham
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Wei Li
University of Alabama at Birmingham
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Neena Xavier
University of Alabama at Birmingham
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Janelle Marie Chiasera
University of Alabama at Birmingham
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    Table 1.

    Detection capability of troponin assays in different clinical presentations of MI

    Clinical Presentation
    Troponin AssayNormalMicronecrosisOvert Necrosis
    Generation 1-3√
    Generation 4√
    Generation 5√√√
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American Society for Clinical Laboratory Science: 31 (4)
American Society for Clinical Laboratory Science
Vol. 31, Issue 4
1 Oct 2018
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Acute Myocardial Infarction: Definition, Diagnosis, and the Evolution of Cardiac Markers
Ana Oliveira, Krystle Glasgow, Floyd Josephat, Robert Estes, Remo George, Tosi Gilford, Samantha Giordano, Heather Hallman, Wei Li, Neena Xavier, Janelle Marie Chiasera
American Society for Clinical Laboratory Science Oct 2018, 31 (4) 200-204; DOI: 10.29074/ascls.2018000687

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Acute Myocardial Infarction: Definition, Diagnosis, and the Evolution of Cardiac Markers
Ana Oliveira, Krystle Glasgow, Floyd Josephat, Robert Estes, Remo George, Tosi Gilford, Samantha Giordano, Heather Hallman, Wei Li, Neena Xavier, Janelle Marie Chiasera
American Society for Clinical Laboratory Science Oct 2018, 31 (4) 200-204; DOI: 10.29074/ascls.2018000687
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  • Article
    • LEARNING OBJECTIVES:
    • ABSTRACT
    • MYOCARDIAL INFARCTION DEFINITION AND CARDIAC MARKERS
    • TROPONIN ASSAYS
    • THE FIFTH-GENERATION OR HIGH-SENSITIVITY TROPONIN ASSAY
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Keywords

  • AMI - acute myocardial infarction
  • AST - aspartate aminotransferase
  • CK - creatine kinase
  • CK-MB - creatine kinase-muscle-brain
  • cTnI - cardiac troponin I
  • cTnT - cardiac troponin T
  • CV - coefficient of variation
  • ECG - electrocardiogram
  • FHS - Framingham Heart Study
  • hs-cTn - high-sensitivity cardiac troponin
  • LBBB - left bundle branch block
  • LDH - lactate dehydrogenase
  • LoD - limit of detection
  • MI - myocardial infarction
  • URL - upper reference limit
  • WHO - World Health Organization
  • myocardial infarction
  • cardiac marker
  • troponin
  • troponin assay
  • high-sensitivity troponin

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