Article Figures & Data
Figures
- Figure 1.
The equation for calculating the traditional Rule of Three is shown.
- Figure 2.
The calculation of the second Rule of Three is presented.
- Figure 3.
The calculation of the relative reticulocyte count by microscopic counting is shown.
- Figure 4.
The formula for calculating a CRC is shown.
- Figure 5.
The calculation of the RPI is shown.
- Figure 6.
The formula to calculate an absolute reticulocyte count is shown.
Tables
- Table 1.
Steps in the methodical interpretation of the red blood cell parameters of the CBC.
1. Interpret the HB value relative to the appropriate reference interval. 2. Interpret the MCV relative to the reference interval. 3. Interpret the MCHC relative to the reference interval. 4. Interpret the RDW relative to the reference interval. 5. Examine the rbc morphology, if available, and correlate morphology with instrument parameters for consistency and quality purposes. Also review for additional diagnostic findings. 6. As a final check on the numerical parameters, examine the RBC, HCT, MCH, and calculate the Rule of Three to ensure that the above interpretations are correct. 7. Use related test results when available, particularly reticulocyte parameters, to verify CBC findings and add diagnostic information. 8. Interpret the rbc parameters for diagnostic significance and correlate with results of wbc and plt parameters. Results Units Reference Interval RBC 3.3 106/μL 3.80-5.20 HB 7.5 g/dL 12.0-15.0 HCT 25 % 35-49 MCV 76 fL 80-100 MCH 22.7 pg 26.0-34.0 MCHC 30.0 % 32-36 RDW 17.5 % 11.5-14.5 Relative reticulocyte count 5.3 % 0.5-2.5 Morphology Anisocytosis, poikilocytosis, hypochromia, and microcytosis Results Units Reference Interval RBC 2.50 106/μL 4.20-6.00 HB 14.5 g/dL 13.5-18.0 HCT 27 % 40-54 MCV 108 fL 80-100 MCH 55.8 pg 26.0-34.0 MCHC 54 % 32-36 RDW 18.0 % 11.5-14.5 Relative reticulocyte count 1.1 0.5-2.5% Morphology Anisocytosis, macrocytosis, and stomatocytes Results Units Reference Interval RBC 2.50 106/μL 4.20-6.00 HB 8.7 g/dL 13.5-18.0 HCT 27 % 40-54 MCV 108 fL 80-100 MCH 34.8 pg 26.0-34.0 MCHC 32.2 % 32-36 RDW 17.8 % 11.5-14.5 Relative reticulocyte count 1.1 % 0.5-2.0 Morphology Anisocytosis, macrocytosis, and stomatocytes Results Units Reference Interval RBC 1.50 106/μL 3.80-5.10 HB 9.5 g/dL 11.5-15.0 HCT 16.5 % 34-44 MCV 110 fL 80-100 MCH 63.3 pg 27.0-34.0 MCHC 57.6 % 32-36 RDW 16.0 % 11.7-15.0 Relative reticulocyte count 12.3 % 0.5-2.0 Absolute reticulocyte count 181.5 103/μL 20-115 Immature reticulocyte fraction 19.5 % 2.0-16.0 Morphology Spherocytosis, slight anisocytosis, clumps of RBCs, and polychromasia Results Units Reference Interval RBC 3.3 106/μL 3.80-5.10 HB 9.5 g/dL 11.5-15.0 HCT 29 % 34-44 MCV 93 fL 80-100 MCH 29 pg 27.0-34.0 MCHC 33 % 32-36 RDW 16.0 % 11.7-15.0 Relative reticulocyte count 5.5 % 0.5-2.0 Absolute reticulocyte count 181 103/μL 20-115 Immature reticulocyte fraction 19.5 % 2.0-16.0 Morphology Spherocytosis, slight anisocytosis, and polychromasia
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