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Research ArticleResearch and Reports

Globalization and Antimicrobial Resistance: A Moving Target

Rodney E. Rohde and Ryan P. McNamara
American Society for Clinical Laboratory Science April 2018, 31 (2) 88-94; DOI: https://doi.org/10.29074/ascls.2018000489
Rodney E. Rohde
Texas State University
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Ryan P. McNamara
The University of North Carolina at Chapel Hill School of Medicine
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    Figure 1.

    The bottleneck effect. A population of a pathogen is exposed to an antimicrobial. The majority of the pathogen population contains no resistance, but a fraction does (green) and can flow through the bottleneck. This population can then propagate, leading to the rise of AMR in that particular pathogen.

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    Figure 2.

    The rise in the population in the United States and urbanization. (A) The United States has seen triple the population growth in the past 100 years. (B) The percentage of the US population living in urban areas has increased dramatically in the past 100 years. All data was obtained from the publicly accessible www.census.gov.

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    Figure 3.

    Increase in global travel and tourism, as predicted in the early 2000s by the World Tourism Organization.

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American Society for Clinical Laboratory Science: 31 (2)
American Society for Clinical Laboratory Science
Vol. 31, Issue 2
1 Apr 2018
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Globalization and Antimicrobial Resistance: A Moving Target
Rodney E. Rohde, Ryan P. McNamara
American Society for Clinical Laboratory Science Apr 2018, 31 (2) 88-94; DOI: 10.29074/ascls.2018000489

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Globalization and Antimicrobial Resistance: A Moving Target
Rodney E. Rohde, Ryan P. McNamara
American Society for Clinical Laboratory Science Apr 2018, 31 (2) 88-94; DOI: 10.29074/ascls.2018000489
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Keywords

  • AMR - antimicrobial resistance
  • HAI - healthcare-associated infection
  • HIV - human immunodeficiency virus
  • MRSA - methicillin-resistant Staphylococcus aureus
  • Mtb - Mycobacterium tuberculosis
  • PBP2A - penicillin-binding protein 2A
  • WWII - World War II
  • antibiotic resistance
  • antimicrobial resistance
  • globalization
  • healthcare-associated infections
  • population mobility
  • urbanization

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