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Research ArticleResearch and Reports

Troponin Structure and Function in Health and Disease

Samantha Giordano, Robert Estes, Wei Li, Remo George, Tosi Gilford, Krystle Glasgow, Heather Hallman, Floyd Josephat, Ana Oliveira, Neena Xavier and Janelle M. Chiasera
American Society for Clinical Laboratory Science October 2018, 31 (4) 192-199; DOI: https://doi.org/10.29074/ascls.2018000679
Samantha Giordano
University of Alabama at Birmingham
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Robert Estes
University of Alabama at Birmingham
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Wei Li
University of Alabama at Birmingham
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Remo George
University of Alabama at Birmingham
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Tosi Gilford
University of Alabama at Birmingham
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Krystle Glasgow
University of Alabama at Birmingham
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Heather Hallman
University of Alabama at Birmingham
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Floyd Josephat
University of Alabama at Birmingham
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Ana Oliveira
University of Alabama at Birmingham
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Neena Xavier
University of Alabama at Birmingham
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Janelle M. Chiasera
University of Alabama at Birmingham
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Article Information

vol. 31 no. 4 192-199
DOI 
https://doi.org/10.29074/ascls.2018000679

Published By 
American Society for Clinical Laboratory Science
Print ISSN 
0894-959X
Online ISSN 
1945-3574
History 
  • Received July 11, 2018
  • Accepted November 27, 2018
  • Published online February 7, 2023.

Copyright & Usage 
© 2018 © 2018 The American Society for Clinical Laboratory Science American Society for Clinical Laboratory Science

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American Society for Clinical Laboratory Science: 31 (4)
American Society for Clinical Laboratory Science
Vol. 31, Issue 4
1 Oct 2018
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Troponin Structure and Function in Health and Disease
Samantha Giordano, Robert Estes, Wei Li, Remo George, Tosi Gilford, Krystle Glasgow, Heather Hallman, Floyd Josephat, Ana Oliveira, Neena Xavier, Janelle M. Chiasera
American Society for Clinical Laboratory Science Oct 2018, 31 (4) 192-199; DOI: 10.29074/ascls.2018000679

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Troponin Structure and Function in Health and Disease
Samantha Giordano, Robert Estes, Wei Li, Remo George, Tosi Gilford, Krystle Glasgow, Heather Hallman, Floyd Josephat, Ana Oliveira, Neena Xavier, Janelle M. Chiasera
American Society for Clinical Laboratory Science Oct 2018, 31 (4) 192-199; DOI: 10.29074/ascls.2018000679
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Jump to section

  • Article
    • LEARNING OBJECTIVES
    • ABSTRACT
    • INTRODUCTION
    • STRIATED MUSCLE STRUCTURE
    • TROPONIN IN MUSCLE CONTRACTION
    • TROPONIN-CAUSING CARDIOMYOPATHIES
    • DEGRADATION OF TROPONIN IN TISSUE AND RELEASE INTO SERUM
    • TROPONIN AS A DIAGNOSTIC AND PROGNOSTIC BIOMARKER
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

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Keywords

  • ADP - adenosine diphosphate
  • ATP - adenosine triphosphate
  • ATPase - adenosine triphosphatase
  • Ca2+ - calcium
  • cTn - cardiac troponin
  • cTnC - cardiac troponin-C
  • cTnI - cardiac troponin-I
  • cTnT - cardiac troponin-T
  • DCM - dilated cardiomyopathy
  • fsTnC - fast twitch skeletal troponin-C
  • fsTnI - fast twitch skeletal troponin-I
  • fsTnT - fast twitch troponin-T
  • HCM - hypertrophic cardiomyopathy
  • Mg2+ - magnesium ion
  • MI - myocardial infarction
  • mRNA - messenger RNA
  • PKA - protein kinase A
  • RCM - restrictive cardiomyopathy
  • ssTnI - slow twitch skeletal troponin-I
  • ssTnT - slow twitch skeletal troponin-T
  • Tm - tropomyosin
  • Tn - troponin
  • TnC - troponin-C
  • TnI - troponin-I
  • TnT - troponin-T
  • troponin
  • high-sensitivity troponin assays
  • myocardial infarction

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